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GenoQuick®-technology

Your rapid technology with high sensitivity and maximum specificity for fast and reliable detection of the HLA-B27 allele. DNA or RNA is isolated from the specimen and detected as quickly as possible on a dipstick.

Following DNA isolation, nucleic acids are selectively replicated in an amplification reaction.

Hybridization

In the thermocycler, the amplicons are thermally denatured and hybridized with specific probes. These specific probes additionally have a gold binding site.  




Gold binding and complex binding

The amplicon-probe hybrid is marked with gold later on the test strip. Using a lateral flow buffer system the marked complex reaches a specific binding site on the test strip and attaches itself there.

Evaluation

This reaction causes a visible band on the strip. Detection using this “dipstick” method takes only 10 minutes, such that a visible result is available as quickly as possible. Evaluating the test is very straightforward: If the specific band appears, the pathogen or genetic marker being tested is present in the specimen.

 

Your benefits with the GenoQuick®-technology

  • Definite result: internal controls document the validity of the results and ensure accurate test execution.
  • Rapid result: detection takes place within 10 minutes on the test strip. Overall a valid result is available within only 2.5 to 3 hours.
  • Cost-effective: the GenoQuick® technology does not require any costly equipment. Thus a cost-effective set-up is possible even for smaller laboratories.
  • Simple evaluation:  detection of the pathogen or genetic marker being tested occurs via a single band on the test strip. The result can be read out at a glance.
  • User-friendly: the GenoQuick® technology does not require significant pipette use and is therefore optimally suited for routine use.

Download flyer GenoQuick® HLA-B27