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HyBeacon technology

Your innovative technology with high sensitivity and specificity. DNA or RNA is isolated from the specimen and detected with fluorescence labeled probes.


Following DNA isolation the extracted nucleic acid is selectively amplified in the  FluoroCycler®.
 

HyBeacon Probes – Detection via Fluorescence Labeling

  HyBeacon probes are single-stranded fluorescence labeled probes complementary to the amplified nucleic acid. In unbound condition of the HyBeacon probes, the fluorophore can not emit fluorescence.
 
After hybridization with the amplicon, excitation and measurement of fluorescence is possible.    
  During the subsequent melting curve analysis the HyBeacon probes and the amplicon separate at a specific temperature. This leads to single-stranded probes and immediately to a decrease of fluorescence.
 

Evaluation and Presentation of Results – Reliable Results at a Glance

The decrease of fluorescence is measured in the FluoroCycler® and displayed as a melting curve.
 
 
  The test specific software evaluates the melting curve and displays the results – at one glance. This ensures convenient interpretation of the results. 

 Your benefits with the HyBeacon technology

  • Reliable Diagnostics from one Source:  From nucleic acid extraction to result, we offer you all the necessary components for your routine laboratory testing.
  • Innovative: The HyBeacon technology provides fast and reliable results for efficient diagnostics in your laboratory.
  • Maximum of Automation: The combination of fully automated nucleic acids extraction and subsequent amplification with fluorescence based detection in the FluoroCycler® saves time-consuming hands on time.
  • Reliable Results at one Glance: The test specific evaluation software of the FluoroCycler® displays the results clearly, providing a guaranteed convenient result interpretation.
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