Mycobacteria product series
You can get the perfect solution for every problem with our extensive mycobacteria product series. Our molecular genetic test systems allow stepwise diagnostics according to your needs. No matter if you have a high or low sample throughput, prefer manual or automated procedures, our test systems are the right choice.
We offer a simple and sensitive test system for an efficient TB screening directly from patient specimens.
If it is suspected that a TB infection might be caused by resistant bacteria, continuative diagnostics are possible in order to quickly and reliably detect multiresistant (MDR) or extensively resistant (XDR) tuberculosis. According to the World Health Organization (WHO) tuberculosis is defined as MDR-TB if the pathogen is resistant to isoniazid and rifampicin, the two most effective first line drugs. With our well-established test system GenoType MTBDRplus, which is used worldwide but especially in countries with high TB prevalence, resistances to rifampicin and isoniazid can reliably be detected. It even allows the discrimination between low and high level resistance to isoniazid, so that the best therapy can be chosen. In case of XDR-TB therapeutic possibilities are limited. These strains are not only resistant to rifampicin and isoniazid but also to an injectable second-line drug and to fluoroquinolones. Here our test system GenoType MTBDRsl can be helpful as it detects resistances to fluoroquinolones, aminoglycosides/cyclic peptides (and ethambutol) directly from patient specimens and culture samples.
M. tuberculosis complex
You want to know exactly which member of the M. tuberculosis complex you are dealing with? This sounds like GenoType MTBC is your method of choice. Starting from a positive culture sample, this test allows quick and reliable pathogen differentiation.
Nontuberculous mycobacteria (NTM)
For diagnostics and treatment it is extremely important to discriminate tuberculous and nontuberculous mycobacteria. We offer a variety of test systems for reliable differentiation of mycobacteria belonging to M. tuberculosis complex from NTM as well as for detection of numerous clinically relevant NTM. These test systems can easily be combined and thus facilitate your work whilst saving valuable time.
Nontuberculous mycobacteria are becoming more and more important as the number of infections increases, especially in countries with low TB prevalence. NTM can cause serious diseases. As they can ubiquitously be found in the environment, it is difficult to reliably diagnose NTM infections. Furthermore, there is no standard therapy. It often depends on the species and is hindered by antibiotic resistances. In order to choose the therapy it is important to know the species and its sensitivities to certain antibiotics. Our test system GenoType NTM-DR gives you a time benefit as it simultaneously detects the most important NTM species and their resistances to macrolides and aminogylcosides.
Leprosy is caused by Mycobacterium leprae and can still be found in developing countries. As M. leprae cannot be cultivated like other mycobacteria, molecular techniques are the method of choice for reliable diagnostics. With our test system GenoType LepraeDR you can identify M. leprae and its resistances to rifampicin, ofloxacin and dapsone directly from patient specimens.
With our mycobacteria product series we want to contribute to the fight against tuberculosis, mycobacteriosis and leprosy. We closely cooperate with reference centers, universities, public authorities and non-governmental organizations worldwide when developing new test systems or improving the existing ones. Our tests are designed to enable laboratories to perform reliable, user-friendly and modern diagnostics in order to heal patients and to hinder the further spread of mycobacteria.
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Mycobacteria: Tuberculosis, NTM and leprosy
Diagnostics of tuberculosis