GenoQuick^® HLA-B27

Your test system for the definite detection of the HLA-B27 gene

Over 90% of all patients with ankylosing spondylitis carry the HLA-B27 gene, which however is only present in 8% of the “healthy” population. Thus the molecular genetic detection of HLA-B27 has a very high diagnostic significance for the probability of developing ankylosing spondylitis.
Ankylosing spondylitis is a chronic rheumatic disease which primarily affects the spine. The early symptomatology of the disease leads to movement limitations of the lumbar spine. Further on in the course of the disease, the symptoms may worsen to the point of hardening of the bones of the spine.
The fist signs of the disease are frequently nonspecific and are generally not associated with the disease. There is generally a time period of 5-10 years between the initial symptoms and a definite diagnosis. However, an early diagnosis is of crucial importance, since the course of the disease can be influenced better when the disease is diagnosed early on.

Based on the high diagnostic significance, it is recommended that all patients with inflammatory back pain undergo an HLA-B27 determination. Along with the clarification of additional parameters, for example, the presence of a positive family history, the test result makes a definite diagnosis possible.

Our GenoQuick^® HLA-B27 test system offers you definitive and easy determination of the HLA-B27 gene and saves crucial time through early diagnosis of the patient.

Your benefits with GenoQuick^® HLA-B27

• Definite result: all relevant subtypes of HLA-B27 are detected. This allows for a definite diagnosis.
• No living cells are needed for detection: in contrast to flow cytometry, molecular genetic detection allows for samples to also be stored over a longer period of time. In this way, smaller production runs can also be efficiently processed.
• Simple evaluation: the presence of the HLA-B27 gene is shown by a single band on the test strip and can thus be seen at a glance.

At a glance
Rapid molecular genetic assay for detection of the HLA-B27 gene

Starting material:
EDTA/Citrate blood

DNA Isolation:
GENO•CARD or
GenoType DNA Isolation Kit

Order number: 
12 tests  No. 311
96 tests  No. 31196